The PureBoost™ EVO mRNA contains a codon-optimized nucleotide sequence of erythropoietin (EPO) protein, which was originally isolated from homo sapiens. The protein promotes red blood cell production, or erythropoiesis in the bone marrow.
- mRNA length : 879
- Concentration: 1mg/ml
- Buffer: 1 mM sodium citrate, pH 6.5
Cellerna mRNAs are produced via PureBoost™ technology which maximizes protein expression and minimizes mRNA immunogenicity. PureBoost™ is a proprietary technology which combines novel advanced capping and ultra-purification processes of in vitro-transcribed mRNAs that have been optimized for robust protein expression. Uniform polyadenylation (100 bp polyA-tail) and almost perfect capping (Cap1 > 98%) mimic natural mRNA and ensure efficient translation. Sequence engineering or chemical modification reduces the innate antiviral response to single-stranded mRNA.
PureBoost™ EPO mRNA
- Gene Name : EPO
- Species: Homo sapiens
- Encoded protein: EPO erythropoietin
- Function : Reporter, CRISPR
- Protein Sequence
- Codon Optimization: Yes
- Application: Positive control for mRNA transfections, CRISPR