PureBoost™ Cas9 mRNA encodes the Cas9 protein, which is employed to perform the DNA cleavage at the genome editing system.
- mRNA length : 4549 bp
- Concentration: 1mg/ml
- Buffer: 1 mM sodium citrate, pH 6.5
Cellerna mRNAs are produced via PureBoost™ technology which maximizes protein expression and minimizes mRNA immunogenicity. PureBoost™ is a proprietary technology which combines novel advanced capping and ultra-purification processes of in vitro-transcribed mRNAs that have been optimized for robust protein expression. Uniform polyadenylation (100 bp polyA-tail) and almost perfect capping (Cap1 > 98%) mimic natural mRNA and ensure efficient translation. Sequence engineering or chemical modification reduces the innate antiviral response to single-stranded mRNA.
PureBoost™ Cas9 mRNA
- Gene Name : casA
- Species: Escherichia coli
- Encoded protein: Cas9
- Protein Sequence
- Codon Optimization: Yes
- Application: CRISPR, Immunotherapeutics, Recombinases